A template wizard for the cocreation of machine-readable data-reporting to harmonize the evaluation of (nano)materials

Nina Jeliazkova, Eleonora Longhin, Naouale El Yamani, Elise Rundén-Pran, Elisa Moschini, Tommaso Serchi, Ivana Vinković Vrček, Michael J Burgum, Shareen H Doak, Mihaela Roxana Cimpan, Ivan Rios-Mondragon, Emil Cimpan, Chiara L Battistelli, Cecilia Bossa, Rositsa Tsekovska, Damjana Drobne, Sara Novak, Neža Repar, Ammar Ammar, Penny NymarkVeronica Di Battista, Anita Sosnowska, Tomasz Puzyn, Nikolay Kochev, Luchesar Iliev, Vedrin Jeliazkov, Katie Reilly, Iseult Lynch, Martine Bakker, Camila Delpivo, Araceli Sánchez Jiménez, Ana Sofia Fonseca, Nicolas Manier, María Luisa Fernandez-Cruz, Shahzad Rashid, Egon Willighagen, Margarita D Apostolova, Maria Dusinska

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Abstract

Making research data findable, accessible, interoperable and reusable (FAIR) is typically hampered by a lack of skills in technical aspects of data management by data generators and a lack of resources. We developed a Template Wizard for researchers to easily create templates suitable for consistently capturing data and metadata from their experiments. The templates are easy to use and enable the compilation of machine-readable metadata to accompany data generation and align them to existing community standards and databases, such as eNanoMapper, streamlining the adoption of the FAIR principles. These templates are citable objects and are available as online tools. The Template Wizard is designed to be user friendly and facilitates using and reusing existing templates for new projects or project extensions. The wizard is accompanied by an online template validator, which allows self-evaluation of the template (to ensure mapping to the data schema and machine readability of the captured data) and transformation by an open-source parser into machine-readable formats, compliant with the FAIR principles. The templates are based on extensive collective experience in nanosafety data collection and include over 60 harmonized data entry templates for physicochemical characterization and hazard assessment (cell viability, genotoxicity, environmental organism dose-response tests, omics), as well as exposure and release studies. The templates are generalizable across fields and have already been extended and adapted for microplastics and advanced materials research. The harmonized templates improve the reliability of interlaboratory comparisons, data reuse and meta-analyses and can facilitate the safety evaluation and regulation process for (nano) materials.

OriginalsprogEngelsk
TidsskriftNature protocols
Vol/bind19
Udgave nummer9
Sider (fra-til)2642-2684
Antal sider43
ISSN1750-2799
DOI
StatusUdgivet - sep. 2024

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