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Ph.d.-vejledning: Maternal stress at work and in private life during pregnancy: Implications for development of asthma and other allergic diseases in their children

Activity: Other

Description

Asthma is the most common chronic disease in children, and despite much
research, the etiology is poorly understood. This thesis aimed to extend the current knowledge of preconception, prenatal, and early life exposures and the risk of childhood asthma. This was examined by addressing occupational exposures of parents before conception and the association with the risk of asthma in their children. Followed by the examination of the association between maternal stressors during pregnancy (at work and in private life) and the development of asthma in the child. Finally, stressful experiences in early childhood relative to the risk of developing asthma were explored. Across studies, the impact of sex on the risk of asthma was investigated. Furthermore, trajectories of childhood asthma phenotypes and validation of self-reported allergy among asthmatics were explored.

Four cohort studies and one validation study were conducted, based on the Danish National Birth Cohort (DNBC), the Respiratory Health in Northern Europe, Spain and Australia (RHINESSA) generation study, the Melbourne Atopy Cohort Study (MACS), the Tasmanian Longitudinal Health Study (TAHS) and nationwide registers in Denmark. (Kathrine Pape Madsen)
Period2017 → 2020
Held atInstitut for Folkesundhed, Aarhus Universitet, Aarhus, Danmark., Denmark
Degree of RecognitionNational

NFA controlled keywords

  • 04 Chemical working environment, toxicology, nano safety and microbiology
  • 06 Psychosocial working environment
  • Toxicology
  • Epidemiology
  • Allergy

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