Long working hours and cancer risk: a multi-cohort study

K. Heikkila; S.T. Nyberg; I.E.H. Madsen; Vroome E. de; L. Alfredsson; Jakob Bue Bjørner; Finn Hermann M Burr; Marianne Borritz; R. Erbel; J.E. Ferrie; E.I. Fransson; G.A. Geuskens; W.E. Hooftman; I.L. Houtman; K.H. Jockel; A. Knutsson; M. Koskenvuo; T. Lunau; M.L. Nielsen; M. Nordin; T. Oksanen; Jan Hyld Pejtersen; J. Pentti; M.J. Shipley; A. Steptoe; S.B. Suominen; T. Theorell; J. Vahtera; P.J. Westerholm; H. Westerlund; N. Dragano; Reiner Ernst Rugulies; I. Kawachi; G.D. Batty; A. Singh-Manoux; M. Virtanen; M. Kivimaki

doi:10.1038/bjc.2016.9

Long working hours and cancer risk: a multi-cohort study

K. Heikkila
, S.T. Nyberg
, I.E.H. Madsen
, Vroome E. de
, L. Alfredsson
, Jakob Bue Bjørner
, Finn Hermann M Burr
, Marianne Borritz
, R. Erbel
, J.E. Ferrie
, E.I. Fransson
, G.A. Geuskens
, W.E. Hooftman
, I.L. Houtman
, K.H. Jockel
, A. Knutsson
, M. Koskenvuo
, T. Lunau
, M.L. Nielsen
, M. Nordin

T. Oksanen, Jan Hyld Pejtersen, J. Pentti, M.J. Shipley, A. Steptoe, S.B. Suominen, T. Theorell, J. Vahtera, P.J. Westerholm, H. Westerlund, N. Dragano, Reiner Ernst Rugulies, I. Kawachi, G.D. Batty, A. Singh-Manoux, M. Virtanen, M. Kivimaki

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

[Open access]BACKGROUND: Working longer than the maximum recommended hours is associated with an increased risk of cardiovascular disease, but the relationship of excess working hours with incident cancer is unclear. METHODS: This multi-cohort study examined the association between working hours and cancer risk in 116 462 men and women who were free of cancer at baseline. Incident cancers were ascertained from national cancer, hospitalisation and death registers; weekly working hours were self-reported. RESULTS: During median follow-up of 10.8 years, 4371 participants developed cancer (n colorectal cancer: 393; n lung cancer: 247; n breast cancer: 833; and n prostate cancer: 534). We found no clear evidence for an association between working hours and the overall cancer risk. Working hours were also unrelated the risk of incident colorectal, lung or prostate cancers. Working 55 h per week was associated with 1.60-fold (95% confidence interval 1.12-2.29) increase in female breast cancer risk independently of age, socioeconomic position, shift- and night-time work and lifestyle factors, but this observation may have been influenced by residual confounding from parity. CONCLUSIONS: Our findings suggest that working long hours is unrelated to the overall cancer risk or the risk of lung, colorectal or prostate cancers. The observed association with breast cancer would warrant further research.British Journal of Cancer advance online publication, 18 February 2016; doi:10.1038/bjc.2016.9 www.bjcancer.com

Original language	Danish
Journal	British Journal of Cancer
Volume	114
Issue number	7
Pages (from-to)	813-818
Number of pages	6
ISSN	0007-0920
DOIs	https://doi.org/10.1038/bjc.2016.9
Publication status	Published - 2016

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10.1038/bjc.2016.9

IPD-Work: Work-related psychosocial factors and health in subgroups.
Rugulies, R. (Project Manager), Madsen, I. E. H. (Project Participant) & Rugulies, R. (Project Participant)
01/04/2010 → 31/12/2020
Project: Research

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Heikkila, K., Nyberg, S. T., Madsen, I. E. H., de, V. E., Alfredsson, L., Bjørner, J. B., Burr, F. H. M., Borritz, M., Erbel, R., Ferrie, J. E., Fransson, E. I., Geuskens, G. A., Hooftman, W. E., Houtman, I. L., Jockel, K. H., Knutsson, A., Koskenvuo, M., Lunau, T., Nielsen, M. L., ... Kivimaki, M. (2016). Long working hours and cancer risk: a multi-cohort study. British Journal of Cancer, 114(7), 813-818. https://doi.org/10.1038/bjc.2016.9

@article{25d1823c82aa4fe88f0ddee425742095,

title = "Long working hours and cancer risk: a multi-cohort study",

abstract = "[Open access]BACKGROUND: Working longer than the maximum recommended hours is associated with an increased risk of cardiovascular disease, but the relationship of excess working hours with incident cancer is unclear. METHODS: This multi-cohort study examined the association between working hours and cancer risk in 116 462 men and women who were free of cancer at baseline. Incident cancers were ascertained from national cancer, hospitalisation and death registers; weekly working hours were self-reported. RESULTS: During median follow-up of 10.8 years, 4371 participants developed cancer (n colorectal cancer: 393; n lung cancer: 247; n breast cancer: 833; and n prostate cancer: 534). We found no clear evidence for an association between working hours and the overall cancer risk. Working hours were also unrelated the risk of incident colorectal, lung or prostate cancers. Working 55 h per week was associated with 1.60-fold (95\% confidence interval 1.12-2.29) increase in female breast cancer risk independently of age, socioeconomic position, shift- and night-time work and lifestyle factors, but this observation may have been influenced by residual confounding from parity. CONCLUSIONS: Our findings suggest that working long hours is unrelated to the overall cancer risk or the risk of lung, colorectal or prostate cancers. The observed association with breast cancer would warrant further research.British Journal of Cancer advance online publication, 18 February 2016; doi:10.1038/bjc.2016.9 www.bjcancer.com",

author = "K. Heikkila and S.T. Nyberg and I.E.H. Madsen and de, \{Vroome E.\} and L. Alfredsson and Bj{\o}rner, \{Jakob Bue\} and Burr, \{Finn Hermann M\} and Marianne Borritz and R. Erbel and J.E. Ferrie and E.I. Fransson and G.A. Geuskens and W.E. Hooftman and I.L. Houtman and K.H. Jockel and A. Knutsson and M. Koskenvuo and T. Lunau and M.L. Nielsen and M. Nordin and T. Oksanen and Pejtersen, \{Jan Hyld\} and J. Pentti and M.J. Shipley and A. Steptoe and S.B. Suominen and T. Theorell and J. Vahtera and P.J. Westerholm and H. Westerlund and N. Dragano and Rugulies, \{Reiner Ernst\} and I. Kawachi and G.D. Batty and A. Singh-Manoux and M. Virtanen and M. Kivimaki",

note = "SUBMISSIONYEAR:2016",

year = "2016",

doi = "10.1038/bjc.2016.9",

language = "Dansk",

volume = "114",

pages = "813--818",

journal = "British Journal of Cancer",

issn = "0007-0920",

publisher = "Springer Nature",

number = "7",

}

Heikkila, K, Nyberg, ST, Madsen, IEH, de, VE, Alfredsson, L, Bjørner, JB, Burr, FHM, Borritz, M, Erbel, R, Ferrie, JE, Fransson, EI, Geuskens, GA, Hooftman, WE, Houtman, IL, Jockel, KH, Knutsson, A, Koskenvuo, M, Lunau, T, Nielsen, ML, Nordin, M, Oksanen, T, Pejtersen, JH, Pentti, J, Shipley, MJ, Steptoe, A, Suominen, SB, Theorell, T, Vahtera, J, Westerholm, PJ, Westerlund, H, Dragano, N, Rugulies, RE, Kawachi, I, Batty, GD, Singh-Manoux, A, Virtanen, M & Kivimaki, M 2016, 'Long working hours and cancer risk: a multi-cohort study', British Journal of Cancer, vol. 114, no. 7, pp. 813-818. https://doi.org/10.1038/bjc.2016.9

TY - JOUR

T1 - Long working hours and cancer risk: a multi-cohort study

AU - Heikkila, K.

AU - Nyberg, S.T.

AU - Madsen, I.E.H.

AU - de, Vroome E.

AU - Alfredsson, L.

AU - Bjørner, Jakob Bue

AU - Burr, Finn Hermann M

AU - Borritz, Marianne

AU - Erbel, R.

AU - Ferrie, J.E.

AU - Fransson, E.I.

AU - Geuskens, G.A.

AU - Hooftman, W.E.

AU - Houtman, I.L.

AU - Jockel, K.H.

AU - Knutsson, A.

AU - Koskenvuo, M.

AU - Lunau, T.

AU - Nielsen, M.L.

AU - Nordin, M.

AU - Oksanen, T.

AU - Pejtersen, Jan Hyld

AU - Pentti, J.

AU - Shipley, M.J.

AU - Steptoe, A.

AU - Suominen, S.B.

AU - Theorell, T.

AU - Vahtera, J.

AU - Westerholm, P.J.

AU - Westerlund, H.

AU - Dragano, N.

AU - Rugulies, Reiner Ernst

AU - Kawachi, I.

AU - Batty, G.D.

AU - Singh-Manoux, A.

AU - Virtanen, M.

AU - Kivimaki, M.

N1 - SUBMISSIONYEAR:2016

PY - 2016

Y1 - 2016

N2 - [Open access]BACKGROUND: Working longer than the maximum recommended hours is associated with an increased risk of cardiovascular disease, but the relationship of excess working hours with incident cancer is unclear. METHODS: This multi-cohort study examined the association between working hours and cancer risk in 116 462 men and women who were free of cancer at baseline. Incident cancers were ascertained from national cancer, hospitalisation and death registers; weekly working hours were self-reported. RESULTS: During median follow-up of 10.8 years, 4371 participants developed cancer (n colorectal cancer: 393; n lung cancer: 247; n breast cancer: 833; and n prostate cancer: 534). We found no clear evidence for an association between working hours and the overall cancer risk. Working hours were also unrelated the risk of incident colorectal, lung or prostate cancers. Working 55 h per week was associated with 1.60-fold (95% confidence interval 1.12-2.29) increase in female breast cancer risk independently of age, socioeconomic position, shift- and night-time work and lifestyle factors, but this observation may have been influenced by residual confounding from parity. CONCLUSIONS: Our findings suggest that working long hours is unrelated to the overall cancer risk or the risk of lung, colorectal or prostate cancers. The observed association with breast cancer would warrant further research.British Journal of Cancer advance online publication, 18 February 2016; doi:10.1038/bjc.2016.9 www.bjcancer.com

AB - [Open access]BACKGROUND: Working longer than the maximum recommended hours is associated with an increased risk of cardiovascular disease, but the relationship of excess working hours with incident cancer is unclear. METHODS: This multi-cohort study examined the association between working hours and cancer risk in 116 462 men and women who were free of cancer at baseline. Incident cancers were ascertained from national cancer, hospitalisation and death registers; weekly working hours were self-reported. RESULTS: During median follow-up of 10.8 years, 4371 participants developed cancer (n colorectal cancer: 393; n lung cancer: 247; n breast cancer: 833; and n prostate cancer: 534). We found no clear evidence for an association between working hours and the overall cancer risk. Working hours were also unrelated the risk of incident colorectal, lung or prostate cancers. Working 55 h per week was associated with 1.60-fold (95% confidence interval 1.12-2.29) increase in female breast cancer risk independently of age, socioeconomic position, shift- and night-time work and lifestyle factors, but this observation may have been influenced by residual confounding from parity. CONCLUSIONS: Our findings suggest that working long hours is unrelated to the overall cancer risk or the risk of lung, colorectal or prostate cancers. The observed association with breast cancer would warrant further research.British Journal of Cancer advance online publication, 18 February 2016; doi:10.1038/bjc.2016.9 www.bjcancer.com

U2 - 10.1038/bjc.2016.9

DO - 10.1038/bjc.2016.9

M3 - Tidsskriftartikel

SN - 0007-0920

VL - 114

SP - 813

EP - 818

JO - British Journal of Cancer

JF - British Journal of Cancer

IS - 7

ER -

Long working hours and cancer risk: a multi-cohort study

Abstract

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Projects

IPD-Work: Work-related psychosocial factors and health in subgroups.

Cite this