Work-related violence and depressive disorder among 955,573 employees followed for 6.99 million person-years. The Danish Work Life Course Cohort study: Work-related violence and depression

Ida E H Madsen; Annemette Coop Svane-Petersen; Anders Holm; Hermann Burr; Elisabeth Framke; Maria Melchior; Naja Hulvej Rod; Børge Sivertsen; Stephen Stansfeld; Jeppe Karl Sørensen; Marianna Virtanen; Reiner Rugulies

doi:10.1016/j.jad.2021.03.065

Work-related violence and depressive disorder among 955,573 employees followed for 6.99 million person-years. The Danish Work Life Course Cohort study: Work-related violence and depression

Ida E H Madsen
, Annemette Coop Svane-Petersen
, Anders Holm
, Hermann Burr
, Elisabeth Framke
, Maria Melchior
, Naja Hulvej Rod
, Børge Sivertsen
, Stephen Stansfeld
, Jeppe Karl Sørensen
, Marianna Virtanen
, Reiner Rugulies

Unit Psychosocial Factors and Mental Health, Federal Institute for Occupational Safety and Health, Berlin, Germany.
Social Epidemiology Research Group, Institut Pierre Louis d'Épidémiologie et de Santé Publique (IPLESP), INSERM UMR_S 1136, Paris, France.
Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Centre for Psychiatry, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Rockwool International
Western University, London, Canada.
Norwegian Institute of Public Health, Bergen, Norway.
Department of Research and Innovation, Helse Fonna HF, Haugesund, Norway.
Department of Mental Health, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.
University of Eastern Finland
Division of Insurance Medicine, Karolinska Institutet, Stockholm, Sweden.
Department of Psychology, University of Copenhagen, Copenhagen, Denmark

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

BACKGROUND: We examined the association between probability of work-related violence and first diagnosis of depressive disorder whilst accounting for the potential selection of individuals vulnerable to depression into occupations with high probability of work-related violence.

METHODS: Based on a pre-published study protocol, we analysed nationwide register data from the Danish Work Life Course Cohort study, encompassing 955,573 individuals followed from their entry into the workforce, and free from depressive disorder before work-force entry. Depressive disorder was measured from psychiatric in- and outpatient admissions. We measured work-related violence throughout the worklife by the annual average occupational risk of violence exposure. Using Cox proportional hazards regression, we examined the longitudinal association between work-related violence (both past year and cumulative life-long exposure) and first depressive disorder diagnosis, whilst adjusting for numerous confounders including parental psychiatric and somatic diagnoses, childhood socioeconomic position, and health services use before workforce entry.

RESULTS: The risk of depressive disorder was higher in individuals with high probability of past year work-related violence (hazard ratio: 1.11, 95% CI: 1.06-1.16) compared to employees with low probability of exposure, after adjustment for confounders. Among women, associations were robust across industries, whereas among men, associations were limited to certain industries.

LIMITATIONS: Violence was measured on the job group and not the individual level, likely resulting in some misclassification of the exposure.

CONCLUSIONS: Work-related violence may increase the risk of depressive disorder, independent of pre-existing risk factors for depressive disorder. These findings underline the importance of preventing work-related violence.

Original language	English
Journal	Journal of Affective Disorders
Volume	288
Pages (from-to)	136-144
Number of pages	9
ISSN	0165-0327
DOIs	https://doi.org/10.1016/j.jad.2021.03.065
Publication status	Published - 26 Mar 2021

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10.1016/j.jad.2021.03.065

FØLKAT: Emotional demands at work and labour market attachment
Rugulies, R. (Project Manager), Pedersen, J. (Project Participant) & Madsen, I. E. H. (Project Participant)
01/10/2017 → 31/12/2023
Project: Research

File
YA: Psychosocial work environment, health, and labour market affiliation in a (work)life course-perspective
Madsen, I. E. H. (Project Manager), Coop Svane-Petersen, A. (Project Participant), Rugulies, R. (Project Participant), Thomsen, B. L. R. (Project Participant) & Melkevik, O. R. (Project Participant)
01/03/2015 → 31/08/2019
Project: Research
DOC*X: EN -DK JEM: Psykisk og fysisk arb.miljø jobeksponeringsmatrice
Rugulies, R. (Project Manager), Holtermann, A. (Project Participant), Madsen, I. E. H. (Project Participant) & Rugulies, R. (Project Participant)
01/01/2015 → 31/12/2018
Project: Research

Cite this

Madsen, I. E. H., Svane-Petersen, A. C., Holm, A., Burr, H., Framke, E., Melchior, M., Rod, N. H., Sivertsen, B., Stansfeld, S., Sørensen, J. K., Virtanen, M., & Rugulies, R. (2021). Work-related violence and depressive disorder among 955,573 employees followed for 6.99 million person-years. The Danish Work Life Course Cohort study: Work-related violence and depression. Journal of Affective Disorders, 288, 136-144. https://doi.org/10.1016/j.jad.2021.03.065

@article{b59263d200e2481590d0369ae996dca2,

title = "Work-related violence and depressive disorder among 955,573 employees followed for 6.99 million person-years. The Danish Work Life Course Cohort study: Work-related violence and depression",

abstract = "BACKGROUND: We examined the association between probability of work-related violence and first diagnosis of depressive disorder whilst accounting for the potential selection of individuals vulnerable to depression into occupations with high probability of work-related violence.METHODS: Based on a pre-published study protocol, we analysed nationwide register data from the Danish Work Life Course Cohort study, encompassing 955,573 individuals followed from their entry into the workforce, and free from depressive disorder before work-force entry. Depressive disorder was measured from psychiatric in- and outpatient admissions. We measured work-related violence throughout the worklife by the annual average occupational risk of violence exposure. Using Cox proportional hazards regression, we examined the longitudinal association between work-related violence (both past year and cumulative life-long exposure) and first depressive disorder diagnosis, whilst adjusting for numerous confounders including parental psychiatric and somatic diagnoses, childhood socioeconomic position, and health services use before workforce entry.RESULTS: The risk of depressive disorder was higher in individuals with high probability of past year work-related violence (hazard ratio: 1.11, 95\% CI: 1.06-1.16) compared to employees with low probability of exposure, after adjustment for confounders. Among women, associations were robust across industries, whereas among men, associations were limited to certain industries.LIMITATIONS: Violence was measured on the job group and not the individual level, likely resulting in some misclassification of the exposure.CONCLUSIONS: Work-related violence may increase the risk of depressive disorder, independent of pre-existing risk factors for depressive disorder. These findings underline the importance of preventing work-related violence.",

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author = "Madsen, \{Ida E H\} and Svane-Petersen, \{Annemette Coop\} and Anders Holm and Hermann Burr and Elisabeth Framke and Maria Melchior and Rod, \{Naja Hulvej\} and B{\o}rge Sivertsen and Stephen Stansfeld and S{\o}rensen, \{Jeppe Karl\} and Marianna Virtanen and Reiner Rugulies",

note = "Copyright {\textcopyright} 2021. Published by Elsevier B.V.",

year = "2021",

month = mar,

day = "26",

doi = "10.1016/j.jad.2021.03.065",

language = "English",

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Madsen, IEH, Svane-Petersen, AC, Holm, A, Burr, H, Framke, E, Melchior, M, Rod, NH, Sivertsen, B, Stansfeld, S, Sørensen, JK, Virtanen, M & Rugulies, R 2021, 'Work-related violence and depressive disorder among 955,573 employees followed for 6.99 million person-years. The Danish Work Life Course Cohort study: Work-related violence and depression', Journal of Affective Disorders, vol. 288, pp. 136-144. https://doi.org/10.1016/j.jad.2021.03.065

Work-related violence and depressive disorder among 955,573 employees followed for 6.99 million person-years. The Danish Work Life Course Cohort study: Work-related violence and depression. / Madsen, Ida E H; Svane-Petersen, Annemette Coop; Holm, Anders et al.
In: Journal of Affective Disorders, Vol. 288, 26.03.2021, p. 136-144.

Research output: Contribution to journal › Journal article › Research › peer-review

TY - JOUR

T1 - Work-related violence and depressive disorder among 955,573 employees followed for 6.99 million person-years. The Danish Work Life Course Cohort study: Work-related violence and depression

AU - Madsen, Ida E H

AU - Svane-Petersen, Annemette Coop

AU - Holm, Anders

AU - Burr, Hermann

AU - Framke, Elisabeth

AU - Melchior, Maria

AU - Rod, Naja Hulvej

AU - Sivertsen, Børge

AU - Stansfeld, Stephen

AU - Sørensen, Jeppe Karl

AU - Virtanen, Marianna

AU - Rugulies, Reiner

PY - 2021/3/26

Y1 - 2021/3/26

N2 - BACKGROUND: We examined the association between probability of work-related violence and first diagnosis of depressive disorder whilst accounting for the potential selection of individuals vulnerable to depression into occupations with high probability of work-related violence.METHODS: Based on a pre-published study protocol, we analysed nationwide register data from the Danish Work Life Course Cohort study, encompassing 955,573 individuals followed from their entry into the workforce, and free from depressive disorder before work-force entry. Depressive disorder was measured from psychiatric in- and outpatient admissions. We measured work-related violence throughout the worklife by the annual average occupational risk of violence exposure. Using Cox proportional hazards regression, we examined the longitudinal association between work-related violence (both past year and cumulative life-long exposure) and first depressive disorder diagnosis, whilst adjusting for numerous confounders including parental psychiatric and somatic diagnoses, childhood socioeconomic position, and health services use before workforce entry.RESULTS: The risk of depressive disorder was higher in individuals with high probability of past year work-related violence (hazard ratio: 1.11, 95% CI: 1.06-1.16) compared to employees with low probability of exposure, after adjustment for confounders. Among women, associations were robust across industries, whereas among men, associations were limited to certain industries.LIMITATIONS: Violence was measured on the job group and not the individual level, likely resulting in some misclassification of the exposure.CONCLUSIONS: Work-related violence may increase the risk of depressive disorder, independent of pre-existing risk factors for depressive disorder. These findings underline the importance of preventing work-related violence.

AB - BACKGROUND: We examined the association between probability of work-related violence and first diagnosis of depressive disorder whilst accounting for the potential selection of individuals vulnerable to depression into occupations with high probability of work-related violence.METHODS: Based on a pre-published study protocol, we analysed nationwide register data from the Danish Work Life Course Cohort study, encompassing 955,573 individuals followed from their entry into the workforce, and free from depressive disorder before work-force entry. Depressive disorder was measured from psychiatric in- and outpatient admissions. We measured work-related violence throughout the worklife by the annual average occupational risk of violence exposure. Using Cox proportional hazards regression, we examined the longitudinal association between work-related violence (both past year and cumulative life-long exposure) and first depressive disorder diagnosis, whilst adjusting for numerous confounders including parental psychiatric and somatic diagnoses, childhood socioeconomic position, and health services use before workforce entry.RESULTS: The risk of depressive disorder was higher in individuals with high probability of past year work-related violence (hazard ratio: 1.11, 95% CI: 1.06-1.16) compared to employees with low probability of exposure, after adjustment for confounders. Among women, associations were robust across industries, whereas among men, associations were limited to certain industries.LIMITATIONS: Violence was measured on the job group and not the individual level, likely resulting in some misclassification of the exposure.CONCLUSIONS: Work-related violence may increase the risk of depressive disorder, independent of pre-existing risk factors for depressive disorder. These findings underline the importance of preventing work-related violence.

KW - Vold og trusler

U2 - 10.1016/j.jad.2021.03.065

DO - 10.1016/j.jad.2021.03.065

M3 - Journal article

C2 - 33887623

SN - 0165-0327

VL - 288

SP - 136

EP - 144

JO - Journal of Affective Disorders

JF - Journal of Affective Disorders

ER -

Work-related violence and depressive disorder among 955,573 employees followed for 6.99 million person-years. The Danish Work Life Course Cohort study: Work-related violence and depression

Abstract

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Projects

FØLKAT: Emotional demands at work and labour market attachment

YA: Psychosocial work environment, health, and labour market affiliation in a (work)life course-perspective

DOC*X: EN -DK JEM: Psykisk og fysisk arb.miljø jobeksponeringsmatrice

Cite this